Alpha-2-Macroglobulin (A2M) in Utah
A natural protein concentrated from your own blood that traps the enzymes linked to cartilage breakdown in painful joints.
What Is Alpha-2-Macroglobulin?
Alpha-2-macroglobulin, or A2M, is a large protein that circulates naturally in your blood. One of its jobs is to trap and neutralize enzymes that break down tissue.
In an arthritic or injured joint, inflammation releases enzymes that slowly break down cartilage. A2M acts like a net that traps these enzymes. Research suggests that the natural amount of A2M in a damaged joint is often too low to keep up, which is the idea behind concentrating it.
To prepare an A2M treatment, we draw a small amount of your blood and use a special process to concentrate the A2M. We then place it into the painful joint. Because it comes from your own blood, there is no foreign material involved.
Conditions We Commonly Treat
A2M is an emerging therapy, and research is still early. Results vary, and we will talk with you honestly about what to expect.
What to Expect
A2M Questions
Both come from your own blood. PRP concentrates platelets and their growth factors to support repair. A2M concentrates a protective protein that helps trap the enzymes that break down cartilage. They are often used together.
A2M is prepared from your own blood, and its use in joints is considered off-label. Research is still growing, and results vary from person to person.
A2M is usually not covered by insurance. All of our services are HSA and FSA eligible.
Ask Us About A2M
Tell us what is going on, and we will help you find the right next step. We see patients from all over Utah and across the United States at our offices in Springville and Moab.